Please don't feel ashamed? | Mind Body Spirit Journal

Please don?t feel ashamed. Rather, simply be contrite when and where appropriate.

Be vigilant to lessons learned and for ways to apply them.

Be powerful.

Be prepared to make amends in simple, practical ways that you can. Without extreme sacrifice. And from a place of admitted human frailty. From sincere desire. And from love. And do so with a sense of purposefulness and the pride of knowing that you are doing the best you can.

That is much more than most people do.

It is not a crime to be human.

And I?ve never known anyone who gets up in the morning, looks in the mirror and asks, ?Gee, I wonder if I can find a great way to screw up my life today??

Things happen. We misjudge. We misstep. We make mistakes. We learn. We live. We move on.

? ken winston caine, feb. 2, 2013
for Tago. For me. And for you, too?

?

? ?

This entry was posted on Sunday, February 3rd, 2013 at 4:07 pm and is filed under > Achievement, > COACHING -- Personal-Development & Success, > Focus, > Healing, > Healing Power of Forgiveness, > Healing Power of Love, > Healing Power of Self-Image Psychology, > How to Make 'Simple' Serenely Elegant, > Intention, > Living with Depression, > Living with Pain, > Living with Stress, > Maintaining Constructive Attitude and Energy, > Manifesting Your Desires, > Meaning, > On-Purpose Living, > Peace, > Positive Energy, > Positive Spirituality, > School of the Spirit, > Self-Healing, > Spirit of Wellness, > Whole Living, > Wisdom. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

Source: http://www.mindbodyspiritjournal.com/please-dont-feel-ashamed/

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Wall Street retreats from five-year high

NEW YORK (Reuters) - Stocks fell on Monday after a disappointing report on factory orders, retreating from gains in the prior session that left the S&P 500 at a five-year high and the Dow above 14,000.

Investors also grew wary on political uncertainty in the euro zone, leading to a sharp rise in Spanish government bond yields.

Chevron and Wal-Mart were among the biggest drags on the Dow after analyst downgrades.

"S&P technicals are at overbought levels, and risk-off harbingers, such as Spanish 10-year yields, which are much more difficult for central bankers to tame, have bounced off recent lows," said Peter Cecchini, managing director at New York-based Cantor Fitzgerald & Co.

Spanish and Italian bond yields rose, renewing worries about the euro zone's sovereign debt crisis. Spain's prime minister faced calls to resign over a corruption scandal, while a probe of alleged misconduct involving an Italian bank was expected to widen three weeks before a national election.

The benchmark S&P 500 rose on Friday, leaving it roughly 60 points away from its all-time intraday high of 1,576.09, while the Dow's march above 14,000 was the highest for the index since October 2007.

The S&P index <.spx> is up 5.5 percent for the year, with nearly half of the gains coming after U.S. legislators temporarily sidestepped the "fiscal cliff" of automatic tax increases and spending cuts.

Data from the Commerce Department showed overall factory orders rose 1.8 percent in December, below economists' expectations. The report said capital goods orders outside of the defense and aircraft industries, edged 0.3 percent lower. The category is seen as a gauge of U.S. business investment plans.

Economic data has pointed to a modest U.S. recovery, but the data have not been strong enough to upset investor expectations the Federal Reserve will continue its stimulus policy that has buoyed stocks.

The Dow Jones industrial average <.dji> was down 117.19 points, or 0.84 percent, at 13,892.60. The Standard & Poor's 500 Index <.spx> was down 13.72 points, or 0.91 percent, at 1,499.45. The Nasdaq Composite Index <.ixic> was down 37.77 points, or 1.19 percent, at 3,141.33.

The CBOE Volatility index VIX <.vix>, Wall Street's so-called fear gauge, jumped more than 10 percent to 14.48 by afternoon trade.

Chevron Corp dipped 1 percent to $115.34 after UBS cut its rating to neutral, while Wal-Mart Stores Inc shed 1.5 percent to $69.46 after JP Morgan lowered its rating on the world's largest retailer and reduced its price target.

Oracle Corp lost 2.6 percent to $35.28 after the company agreed to buy network gear maker Acme Packet Inc for about $1.9 billion. Acme Packet shares surged 22 percent to $29.20.

Shares of household products company Clorox rose 1.3 percent to $80.23 after quarterly profit beat analysts' estimates as a severe flu season boosted sales of disinfecting wipes.

Earnings are due from Anadarko Petroleum Corp and Yum! Brands Inc , owner of fast-food chains, after the closing bell.

According to Thomson Reuters data, of the 256 companies in the S&P 500 that have reported earnings through Monday morning, 68.4 percent have reported earnings above analyst expectations compared with the 62 percent average since 1994 and the 65 percent average over the past four quarters.

S&P 500 fourth-quarter earnings are expected to rise 4.4 percent, according to the data. That estimate is above the 1.9 percent forecast at the start of earnings season, but well below the 9.9 percent fourth-quarter earnings forecast on October 1.

Herbalife Ltd slumped 3 percent to $34.03 after the New York Post newspaper reported the seller of weight loss products is facing a probe by the Federal Trade Commission.

(Reporting By Angela Moon; Editing by Kenneth Barry and Nick Zieminski)

Source: http://news.yahoo.com/stock-futures-dip-five-highs-data-earnings-tap-122930257--finance.html

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SMI Eye-Tracking 3D Glasses use rim-based cameras to adjust perspective

Can 3D glasses get any less fashionable? Of course they can! And here's some proof. Today, SensoMotoric Instruments (SMI) teased its new Eye-Tracking 3D Glasses, which use a pair of small cameras mounted to the eyeglass rim to keep tabs on your gaze, adjusting perspective as you look about a scene. The rig uses ActiveEye technology from Volfoni, and can detect eye distance as well in order to provide a 3D-viewing experience that's optimized for each user. Adding some optional hardware, including optical targets (as seen in the video after the break), can enable 6D head tacking support, for an even more immersive experience. Naturally, the solution is a bit cumbersome, and while pricing hasn't been announced, we don't expect it to come cheap -- it's definitely something you'd be more likely to see implemented as part of a virtual reality system, rather than a device you'd use at home. So, while you may never see such a product in the flesh, you can still get an idea of how it'll work in the video after the break.

Filed under: Home Entertainment, Wearables

Comments

Source: SMI (PR Newswire)

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/DOb8IE2Dvho/

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SUPER BOWL WATCH: NFL awards, real fun to come

In this photo taken with a fisheye lens, workers put up signage outside the Superdome where tomorrow's NFL Super Bowl XLVII football game between the San Francisco 49ers and Baltimore Ravens will be played, Saturday, Feb. 2, 2013, in New Orleans. (AP Photo/Charlie Riedel)

In this photo taken with a fisheye lens, workers put up signage outside the Superdome where tomorrow's NFL Super Bowl XLVII football game between the San Francisco 49ers and Baltimore Ravens will be played, Saturday, Feb. 2, 2013, in New Orleans. (AP Photo/Charlie Riedel)

Members of the Baltimore Ravens warm up during an NFL Super Bowl XLVII walkthrough on Saturday, Feb. 2, 2013, in the Mercedes-Benz Superdome in New Orleans. The Ravens face the San Francisco 49ers in Super Bowl XLVII on Sunday. (AP Photo/Patrick Semansky)

People walk along Bourbon Street in downtown New Orleans, as revelers gathered in the city's French Quarter, Friday, Feb. 1, 2013. The city kicked off NFL football Super Bowl weekend as it awaits for Sunday's game between the San Francisco 49ers and the Baltimore Ravens at the Superdome. (AP Photo/Julio Cortez)

San Francisco 49ers quarterback Colin Kaepernick (7) warms up during practice in the Superdome on Saturday, Feb. 2, 2013, in New Orleans. The 49ers are scheduled to play the Baltimore Ravens in the NFL Super Bowl XLVII football game on Feb. 3. (AP Photo/Mark Humphrey)

NEW ORLEANS (AP) ? Around the Super Bowl and its host city with journalists from The Associated Press bringing the flavor and details of everything surrounding the game:

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REAL FUN TO COME

The NFL's best have been mingling with celebrities, signing autographs for adoring fans and enjoying all the festivities New Orleans has to offer during Super Bowl weekend. But make no mistake, they'd gladly give that all up.

They'd rather be on the field at the Superdome on Sunday.

Case in point, what New York Giants Eli Manning told Nekesa Mumbi Moody, AP's global lifestyles and entertainment editor, on Saturday:

"I'm not enjoying it as much," he said.

Manning spent Saturday with his dad Archie and brother Peyton, first watching a celebrity flag football game featuring A-listers including Lil Wayne, Snoop Dogg, Katharine McPhee, Deion Sanders, Neil Patrick Harris and more. The family then went to the "2nd Annual NFL Honors" awards Saturday night, where Peyton Manning won AP's NFL Comeback Player of the Year award during a show televised on CBS. The younger Manning said he likes being back in New Orleans, back where he grew up.

But this time last year, he was one night away from winning a Super Bowl and being crowned the game's MVP.

Where would you rather be?

"I'd rather be right now in the hotel room, looking at my playbook, trying to figure out how to win another championship," Eli Manning said.

? Oskar Garcia and Nekesa Mumbi Moody ? http://twitter.com/oskargarcia and http://twitter.com/nekesamumbi

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1 HARBAUGH FAMILY WIN

The Harbaugh family got an early win on Saturday night well before the Super Bowl.

Tom Crean, coach of the No. 3 Indiana men's basketball team, knocked off No. 1 Michigan 81-73 at home. Crean is married to Joani Harbaugh, sister of San Francisco 49ers coach Jim Harbaugh and Baltimore Ravens coach John Harbaugh.

It's the third time in school history the Hoosiers have beaten the No. 1 team at home. When the new AP Top 25 poll comes out Monday, Indiana will likely take back the No. 1 ranking it held for the first seven weeks this season.

The Harbaugh family will finish the weekend with a 2-1 record.

? Michael Marot ? http://twitter.com/apmarot

___

5 KEY PLAYERS: SAN FRANCISCO

We asked AP pro football writer Barry Wilner to pick five key players for each team in this Super Bowl. You'll want to pay attention to these guys on Sunday.

For the Baltimore Ravens, it's Joe Flacco, Ray Rice, Ray Lewis, Paul Kruger and Cary Williams. Now, for the San Francisco 49ers:

Kaepernick, Crabtree, Gore, Aldon Smith, Patrick Willis

?COLIN KAEPERNICK (QB, JERSEY NO. 7): Dynamic player who replaced injured Alex Smith in November and kept the job. Fast with long strides, strong arm, unafraid to throw into tight spots.

?MICHAEL CRABTREE (WR, JERSEY NO. 15): Matured this season and became a true No. 1 receiver. Led team with 85 catches, 1,105 yards and nine TDs. Good after catch, but needs to consider better ball security.

?FRANK GORE (RB, JERSEY NO. 21): Career rushing leader for franchise, as dependable as they come. Strong, can pound through line, but also has quick feet to cut to open space. Had 1,214 rushing yards and eight TDs during season.

?ALDON SMITH (OLB, JERSEY NO. 99): All-Pro sacks machine. Not as good as he needs to be in coverage, but is raw. Then again, why not rush him every play? Great burst off the line, big wingspan and maneuverability.

?PATRICK WILLIS (ILB, JERSEY NO. 52): With apologies to Ray Lewis, Willis is best linebacker in this Super Bowl ? and probably best in entire league. Has been All-Pro in five of six seasons.

? Barry Wilner

___

BROTHERLY ADVICE: THE MANNINGS

Baltimore Ravens coach John Harbaugh and San Francisco 49ers coach Jim Harbaugh are hardly the only high-profile siblings who've squared off in their arena of expertise. The AP is asking some others who can relate how to handle going against a family member in the Super Bowl.

When NFL quarterbacks Eli and Peyton Manning squared off during a regular season game, at least one parent didn't have too hard a time deciding who to root for.

"I knew my mom was going to root for me ? I'm the baby of the family, so that was an easy one," Eli Manning said.

But sibling battles can be tough on parents, the New York Giants quarterback said.

"It's hard to be excited for one child winning a game and also disappointed for the other one that didn't," he said.

As for the Harbaugh brothers: "I think they're just both trying to figure out how to get a win."

Eli's brother Peyton Manning says the Harbaughs have handled the week well, knowing one brother will be happy Sunday night while the other will be disappointed.

"Neither would be in this game if they weren't excellent coaches and no matter what happens tomorrow night, they're still excellent coaches. That's just a matter of fact," Peyton Manning said.

? Nekesa Mumbi Moody and Nancy Armour ? http://twitter.com/nekesamumbi and http://twitter.com/nrarmour

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AWARDS OVER, TIME TO PARTY

Now that the NFL awards have ben doled out, it's time to bring on the celebrity-studded parties on Super Bowl eve.

Here are the headliners for Saturday night in New Orleans:

? Singer-songwriter Stevie Wonder headlines outdoor concert near Wyndham Riverfront Hotel that will also feature Texas guitarist Gary Clark Jr. Wonder's opening act: Grammy-nominated R&B and soul artist Janelle Monae. The closer: French electronic DJ Martin Solveig.

? Justin Timberlake takes stage for his first concert in more than four years during "DIRECTV Super Saturday Night." It's invitation only.

? Chevel Johnson

___

FANTASY CONSIDERATIONS

Many of the millions of Americans who play fantasy football will be watching Sunday's Super Bowl with an eye toward next season's drafts.

But as one fantasy expert warns, don't put too much stock into what you see in the game ? good or bad.

Matthew Berry, an ESPN fantasy analyst nicknamed "The Talented Mr. Roto," said there will be some interesting players on the field from a fantasy perspective, including 49ers quarterback Colin Kaepernick, Baltimore wide receiver Torrey Smith and San Francisco wide receiver Michael Crabtree.

But barring major injury, fantasy owners shouldn't get caught up in how they perform in New Orleans, Berry said.

"I think fantasy owners are smart enough and savvy enough to know that the postseason is something different and it's a very small sample size," Berry says.

Simply put, it takes more games than a Super Bowl to judge whether someone's fantasy worthy.

But if you thought you could be sneaky and nab Kaepernick or Crabtree with a late draft pick next season, think again. The duo's performance throughout the last half of the regular season and the postseason mean they'll go in higher rounds, Berry says.

? Oskar Garcia ? http://twitter.com/oskargarcia

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QUICKQUOTE: AP'S MVP SPEECH

Minnesota running back Adrian Peterson thanked God, his parents, teammates and coaches for propelling him to the Associated Press 2012 NFL Most Valuable Player award.

And he wants to win the hardware again.

"God willing, next year I'll be accepting this award again. Trying to get two or three like Peyton (Manning). Trying to get to your level ... But I won't be there to accept it because I'll be winning with my coach, the most important award, the team award, the Super Bowl."

? Nancy Armour ? http://twitter.com/nrarmour

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STAT OF THE DAY: HALF DON'T CARE WHO WINS

This Super Bowl stat of the day comes by way of Jennifer Agiesta, AP's director of polling: A Seton Hall poll shows 53 percent of Americans don't care who wins on Sunday.

The Seton Hall Sports Poll, conducted Jan. 28-30, shows 26 percent of people rooting for the San Francisco 49ers and 21 percent rooting for the Baltimore Ravens.

One-third of Americans plan to skip Sunday's game.

The poll of 894 randomly selected adults has a margin of error of plus or minus 3.3 percentage points.

? Jennifer Agiesta ? http://twitter.com/jennagiesta

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AP TOPS PEYTON FOR MVP

Minnesota's Adrian Peterson is the NFL's Most Valuable Player as selected by an Associated Press vote.

The running back coming back from major knee surgery beat out Denver quarterback Peyton Manning on Saturday night.

It's Peterson's second award of the night after winning Offensive Player of the Year.

Peterson led the Vikings from a 3-13 mark to 10-6 and a wild-card playoff berth. He is the first running back to win MVP since LaDainian Tomlinson in 2006.

___

PEYTON'S COMEBACK

NFL fans everywhere wondered if Peyton Manning could come back from four neck surgeries after 13 years in Indianapolis without missing a game.

Now he's AP's 2012 NFL Comeback Player of the Year.

Manning sat out 2011, then made Denver one of the league's top teams, guiding the Broncos to the AFC's best record at 13-3.

Manning received 31? votes Saturday from a nationwide panel of 50 media members who regularly cover the league. He easily beat Minnesota Vikings running back Adrian Peterson, who got 17? votes.

? Barry Wilner

___

QUICKQUOTE: RG3

One year in the NFL and Washington Redskins quarterback Robert Griffin III is already an award winner.

He took home AP's NFL Offensive Rookie of the Year honors on Saturday night and promptly warned the league he plans to improve.

"It's truly a blessing to be up there ? to be able to stand, first and foremost," said Griffin, who underwent knee surgery last month.

Next season, "you'll see a better Robert Griffin," he said.

? Barry Wilner

___

PETERSON OFFENSIVE POY

Minnesota running back Adrian Peterson went from major knee surgery to dominating voting in The Associated Press 2012 NFL Offensive Player of the Year award.

It helps that he rushed for 2,109 yards, 9 short of Eric Dickerson's record.

Peterson had 36 of 50 votes; Denver quarterback Peyton Manning had eight.

Peterson scored 12 touchdowns rushing and averaged 6.0 yards per carry.

? Barry Wilner

___

WATT ALMOST SWEEPS

Houston end J.J. Watt just missed being a unanimous pick for AP's 2012 NFL Defensive Player of the Year.

The final vote tally with 50 voters:

Watt, 49. Denver linebacker Von Miller, 1.

Watt is the first Texans player to win the award.

? Barry Wilner

___

INTERIM TO TOP

Bruce Arians is the first interim coach to win the top NFL award from The Associated Press.

He won 2012 Coach of the Year honors Saturday night for his work with the Indianapolis Colts. Arians now is head coach in Arizona.

Arians took charge of the Colts in late September after head coach Chuck Pagano was diagnosed with leukemia. The Colts, 2-14 the previous season, went 9-3 under Arians and made the playoffs.

Pagano coached the final game of the regular season and a wild-card playoff match.

Arians earned 36? votes from a nationwide panel of 50 media members who regularly cover the NFL. Pagano finished second with 5?.

___

KUECHLY WINS DEFENSIVE ROY

Linebacker Luke Kuechly of Carolina has won the Associated Press 2012 NFL Defensive Rookie of the Year award.

Kuechly, a first-round pick from Boston College, led the league with 164 tackles.

He earned 28 votes from a nationwide panel of 50 media members who regularly cover the league. That easily outdistanced Seattle LB Bobby Wagner with 11.

? Barry Wilner

___

RG3 OFFENSIVE ROOKIE OF YEAR

Washington Redskins quarterback Robert Griffin III has been voted the 2012 NFL Offensive Rookie of the Year.

Griffin beat out Indianapolis quarterback Andrew Luck and Seattle quarterback Russell Wilson. He was selected by The Associated Press in balloting by a nationwide panel of the media.

___

FIRED UP

Here's one way to spend your 37th birthday: Flag burning.

That's how Mike Libber of Baltimore showed his loyalty to the Ravens during Friday night festivities on Bourbon Street in New Orleans' French Quarter.

Libber and his friends filled the long but thin balcony at the Voodoo Vibe bar, and asked bar employees to remove a San Francisco 49ers flag dangling next to a Ravens flag.

"Yeah, take that away," Libber said. "Otherwise, I'll burn it. In fact, let me burn it."

Libber eventually scrounged up $60 from his friends and bought the San Francisco flag from a bar manager.

He took it out onto Bourbon Street and began to set it on fire. It didn't quickly light up.

A crowd gathered, some 49ers fans booed. Moments later, with a small part of the flag burning, New Orleans police officers arrived and stopped the shenanigans.

? Julio Cortez ? http://twitter.com/JulioCortez_AP

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WHERE'S BRANGELINA?

New Orleans is crawling with celebrities for the Super Bowl, but Brad Pitt and Angelina Jolie don't appear to be among them.

The windows at the star couple's house in the French Quarter are all closed tight, and there's no sign of their omnipresent security. In fact, the only activity at the house is tourists stopping to take photos.

? Nancy Armour ? http://www.twitter.com/nrarmour

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7 TO HALL, INCLUDING PARCELLS

The Pro Football Hall of Fame will have seven new members.

Coach Bill Parcells, Warren Sapp, Cris Carter, Jonathan Ogden and Larry Allen have all made it to the 2013 class. So have two senior selections, Curley Culp and Dave Robinson.

Five players were eliminated in the final vote: Jerome Bettis, Charles Haley, Andre Reed, Michael Strahan and Aeneas Williams.

Earlier Saturday, the selection committee eliminated Tim Brown, Kevin Greene, Will Shields and former owners Edward DeBartolo Jr. and Art Modell.

___

49ERS WALKTHROUGH

The next time the 49ers step onto the field at the Superdome, it'll be time for the Super Bowl.

San Francisco finished up on-field preparations on Saturday with a 15-minute walkthrough. The team has meetings Saturday night.

Coach Jim Harbaugh said the stadium lights are brighter than they were when the 49ers beat the New Orleans Saints here on Nov. 25, so getting his players adjusted to that was important.

Harbaugh invited family members and friends ? 11 busloads of people ? to attend the short session and come down to the field to pose for photographs.

One person hollered Harbaugh's signature chant from the stands: "Who's got it better than us?"

The rest of the group replied: "No-body!"

The coach smiled.

? Janie McCauley ? http://twitter.com/JanieMcCAP

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RAVENS DONE PRACTICING

Baltimore is done practicing on the field for the Super Bowl.

Team officials, friends and family watched as the Ravens went through a short walkthrough at the Superdome on Saturday afternoon.

The 15-minute session was more of a pep rally than a workout.

Running back Ray Rice playfully tackled his mother on the sideline and guard Marshal Yanda had a video camera attached to the top of his Ravens cap.

John Harbaugh describes his team's work this week as "effective."

"We've gotten everything we've needed to get done, that's the No. 1 thing," Harbaugh said.

___

GLORY, PLUS CASH

The Super Bowl isn't just about the glory ? players for San Francisco and Baltimore both have decent paydays riding on the outcome.

The difference between winning and losing is $44,000, nearly $9,000 less than the median annual household income in the United States from 2007-2011, according to U.S. Census data.

Winning players get $88,000 each, losers get $44,000. That's just cash ? it doesn't count the marketing clout gained by going from NFL player to Super Bowl champion.

Super Bowl paydays have gradually increased the last 30 years after doubling in 1983 to $36,000 for winners.

In the game's first 11 years, winners got $15,000 and losers got $7,500.

? Oskar Garcia ? http://twitter.com/oskargarcia

___

MACKIE COLD ON NY GAME

Add Anthony Mackie to the list of people cold on next year's Super Bowl at the home stadium of New York's teams.

Though the "Gangster Squad" actor now lives in Brooklyn, N.Y., he's from New Orleans and thinks a city like his hometown should get the Super Bowl every year.

Mackie said Friday night at an ESPN Magazine party that he doesn't want to sit outside in 30 degree weather and watch the Super Bowl.

"I want to see the girls in their pretty dresses; I want to hang out with the players. I don't want to be outside in the cold in New Jersey," he continued, stressing that Met Life Stadium, where both the New York Giants and Jets play, is actually in East Rutherford, N.J. "You're not in New York. I have to take a bus from Manhattan all the way to Jersey?"

Though Mackie's Saints didn't make it to the Super Bowl this year, Mackie is still passionate about who he wants to win ? the Baltimore Ravens.

"I will do everything to not see San Francisco win another Super Bowl," he said, hoping for a bit of karma.

? Nekesa Mumbi Moody ? http://twitter.com/nekesamumbi

___

LEAVING HIS MARK

If there are some dents in the Superdome roof, blame San Francisco 49ers punter Andy Lee.

Lee bonked several punts off the roof this week as the 49ers practiced for Sunday's Super Bowl against the Baltimore Ravens. Lee finally lowered the trajectory of his kicks to make sure he got the ball downfield.

"I'm glad he didn't hit those lights," 49ers coach Jim Harbaugh said.

? Nancy Armour ? http://twitter.com/nrarmour

___

PLAYING FOOTBALL, NOT FUTBOL, IN MEXICO

The NFL wants to return to Mexico, though Commissioner Roger Goodell won't say when.

Back in 2005, Azteca Stadium in Mexico City was the site of the league's first regular-season game outside the United States. But the league hasn't been back, despite playing in Toronto and ? now regularly ? in London.

Goodell says the league is perfecting things in England.

"We have to make sure that whenever we do come back to Mexico, and I expect we will, that we do it successfully, with the right kind of television support, fan support and sponsor involvement," Goodell said.

"I would expect if we are successful in the UK, where we thankfully are continuing to grow, that we'll have the opportunity to get back there," Goodell said. "And the sooner, the better for me."

? Nancy Armour ? http://www.twitter.com/nrarmour

___

EDITOR'S NOTE ? "Super Bowl Watch" shows you the Super Bowl and the events surrounding the game through the eyes of Associated Press journalists across New Orleans and around the world. Follow them on Twitter where available with the handles listed after each item.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-02-03-Super%20Bowl%20Watch-Package/id-7a6f987c6f2b4195859dabac874baf11

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Jailed Pussy Riot member suffering headaches, fatigue: bandmate

MOSCOW (Reuters) - One of the jailed members of Russian punk protest collective Pussy Riot has been moved to a prison with a hospital after suffering headaches and fatigue, her bandmate said in remarks broadcast on Friday.

Nadezhda Tolokonnikova, 23, was one of three women sentenced to two years in prison for a "punk prayer" in Russia's main cathedral last February in which they called on the Virgin Mary to rid Russia of Vladimir Putin.

Tolokonnikova was sent to a Corrective Colony No. 14 in the Mordovia region after losing her appeal in October.

"She has been complaining about her health for a long time, and a decision was taken to move her to a neighboring (prison) colony where there is a hospital," her bandmate Yekaterina Samutsevich told Internet and cable channel Dozhd.

She said Tolokonnikova had suffered headaches for months and was exhausted from labor at the prison, where she reportedly has been working at a sewing machine. She said she had been moved to the other prison several days ago.

"The problem is, they don't let her rest after the shift," said Samutsevich. "After the shift, they give them more tasks, and she is just working round the clock. She complains of fatigue, huge fatigue."

Samutsevich said she believed Tolokonnikova was being monitored but not actively treated, and she did not specify whether she was hospitalized at all times. Prison authorities could not immediately be reached.

Tolokonnikova, Samutsevich and Maria Alyokhina were convicted of "hooliganism motivated by religious hatred" for their protest in Moscow's Christ the Saviour cathedral, which the dominant Russian Orthodox Church cast as part of a coordinated attack.

The band said they were protesting the close ties between the government and the church, whose leader praised Putin during his successful campaign for a March 2012 presidential election after four years as prime minister.

Kremlin critics called the jailing of Pussy Riot part of a drive to silence dissent during Putin's new term. He has dismissed Western criticism of their jailing, saying the state must protect the faithful and guard against religious discord.

Samutsevich was freed in October when her sentence was suspended on appeal. Tolokonnikova and Alyokhina have about 13 months left in their sentences, which are counted from their arrests last March.

(Reporting by Steve Gutterman; Editing by Lisa Shumaker)

Source: http://news.yahoo.com/jailed-pussy-riot-member-suffering-headaches-fatigue-bandmate-060720988.html

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Itching for new help for eczema: Recently identified immune cells possible therapeutic target

Itching for new help for eczema: Recently identified immune cells possible therapeutic target

Thursday, January 31, 2013

The increasing incidence of allergic skin diseases, and the accompanying economic burden and heightened risk of developing other allergic conditions, have spurred researchers to look for better ways to control these immune system-based disorders.

Atopic dermatitis, more commonly called eczema, now affects 10 to 20 percent of children in the United States and direct health-care costs exceed $3 billion, according to the National Institute of Arthritis and Musculoskeletal and Skin Diseases. What's more, up to 50 percent of children with atopic dermatitis will develop other allergic diseases, including asthma, a phenomenon termed the "allergic march," the gradual acquisition of co-existing allergic diseases.

David Artis, Ph.D., associate professor of Microbiology, and Brian Kim, M.D., clinical instructor of Dermatology, from the Perelman School of Medicine, University of Pennsylvania, have identified a previously unknown critical role for a recently identified immune cell population in the progression of atopic dermatitis. They describe their findings in the latest issue of Science Translational Medicine.

The team found an accumulation of innate lymphoid cells (ILCs) in the active lesions of patients with atopic dermatitis. Using a mouse model of atopic dermatitis they also showed that mouse ILCs contribute to disease progression. These studies suggest innate lymphoid cells may be a new therapeutic target in treating the development and severity of atopic dermatitis.

Under the Skin

"Like foot soldiers protecting the skin barrier from onslaught, innate lymphoid cells are present in healthy skin and we would predict that these cells play a role in maintaining normal tissue function and perhaps in protecting against microbes on this barrier," says Artis. "However, in chronic inflammatory diseases like atopic dermatitis, unchecked innate lymphoid cell responses can promote inflammation."

Kim adds, "A potential consequence of our more hygienic environment is that immune cells may be left somewhat redundant and so contribute to the increasing incidence of allergic diseases like eczema."

Many studies before the current one in STM have identified immune pathways that activate ILCs in such other tissues as the intestine and lung. "An unexpected finding of the current study is that innate lymphoid cells in the skin appear to be activated and regulated by different pathways," says Kim. "These findings suggest that tissue-specific local signals may regulate their function. This finding may also offer therapeutic potential to selectively target innate lymphoid cells in certain tissues, especially for limiting disease severity."

At present, the first-line therapy for atopic dermatitis remains topical steroids. Unlike other inflammatory diseases like psoriasis and arthritis that can be treated with modern biologic-based therapies, there are no targeted biologic therapies that are approved for use to treat atopic dermatitis.

"Our findings give us hope that new biologic therapies may be designed to treat atopic dermatitis in the future," says Artis.

These studies are part of a new collaboration between basic scientists in Penn's Department of Microbiology and Institute for Immunology, along with clinicians at Penn's Department of Dermatology. These studies are supported by the National Institutes of Health's Clinical and Translational Science Award program, which is administered through Penn's Institute for Translational Medicine and Therapeutics.

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University of Pennsylvania School of Medicine: http://www.uphs.upenn.edu/news/

Thanks to University of Pennsylvania School of Medicine for this article.

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Source: http://www.labspaces.net/126552/Itching_for_new_help_for_eczema__Recently_identified_immune_cells_possible_therapeutic_target

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